The relationship between hypertension and COVID-19 vaccine in the long term and occupational evaluation

Abstract

Introduction: Many cardiovascular complications, especially myocarditis and pericarditis, have been observed with vaccination. One of these cardiovascular complications is hypertension with a rate of 1-5%. Hypertension emerged in the acute period after vaccination and tended to be persistent in patients with advanced age and comorbid diseases. In this study, we aimed to examine the relationship between hematological, biochemical markers and demographic characteristics between healthy individuals who have never been vaccinated or vaccinated and patients with new- onset hypertension.

Material and Method: Patients diagnosed with new-onset hypertension and healthy COVID-19 vaccinated, and non-COVID-19 vaccinated control patients of similar age and number were included in the study. The relationship between hematological, biochemical and demographic data between newly diagnosed hypertension patients and healthy COVID-19 vaccinated, and healthy non-vaccinated patients was examined.

Result: 56.3% of newly diagnosed hypertension patients were female, 46.9% were primary school graduates, 37.5% were housewives, 81.3% had stress in their lives. Hypertension patients were older (p<0.01), had lower hemoglobin levels (p=0.05) and higher LDL-C levels (p<0.01) than healthy unvaccinated patients.

Conclusion: Although it is seen that the cause of hypertension cannot be attributed solely to the vaccine, since the hypertensive group was older, had a higher body mass index, hyperglycemia and hyperlipidemia compared to the healthy group, and the number of patients in the study was small, but being a housewife is the most important occupational group and stress is an important trigger. The majority of vaccinees were primary school graduates. Anemia and LDL elevation were found in hypertensive and vaccinated patients. To the best of our knowledge, it is one of the first studies to examine LDL elevation in vaccinated patients and the relationship between long- term newly diagnosed hypertension and vaccination, although confounding factors cannot be excluded.