Comparison of Clinical Profiles, Angiographic Features and Outcomes of Young and Elderly Patients with ST-Segment Elevation Myocardial Infarction

Abstract

Objective: It is to reveal the differences between clinical, angiographic, in-hospital and one-year follow-up results between young and elderly patients with acute ST-segment elevation myocardial infarction.

Material and Methods: This study was designed retrospectively in two centers. 2891 patients were screened; 260 of which were young. 260 elderly patients were randomly selected among the patients and the differences between both groups were evaluated.

Results: The median age of the young patients was 37 (34-39) years and the median age of the elderly patients was 65 (56-73) years, and male gender was dominant in both groups. Young patients were more likely to be admitted with Killip class 1, while older patients were more likely to be admitted with Killip class 2 (P=0.002). Single-vessel disease was more common in young patients (81.0% vs. 46.3%; P<0.001), while multi-vessel disease was more common in the elderly patients (19.0% vs. 53.7%; P<0.001). In one-year follow-up, all-cause hospitalization was lower in younger patients, but there was no significant difference in mortality between elderly and young patients.

Conclusion: Young patients presenting with ST-segment elevation myocardial infarction were more frequent smokers, obese and dyslipidemic and although in-hospital outcomes were better than the elderly, one-year mortality was similar to those of the elderly.