Central nervous system involvement of chronic lymphocytic leukaemia: A rare case report

Authors

DOI:

https://doi.org/10.32552/2024.ActaMedica.994

Keywords:

chronic lymphocytic leukemia, central nervous system, cerebralspinal fluid

Abstract

Central nervous system (CNS) involvement in chronic lymphocytic leukemia (CLL) is unfamiliar. The diagnosis is delayed commonly, because of underdiagnosis or subclinical symptoms. We describe a 80-year-old woman with a previous diagnosis of CLL who presented to the emergency service with tonic clonic seizure. The new therapies, eg, ibrutinib and venetoclax, can be effective treatment strategies for CLL with CNS involvement. In our case, treatment with ibrutinib led to a resolution of the cerebralspinal fluid (CSF) neoplastic infiltration, but the patient died afterwards.

Downloads

Download data is not yet available.

Downloads

Published

2024-06-30

How to Cite

1.
Koyun D, Bozkurt KU, Abbaszade N, Yılmaz R, Topçuoğlu P. Central nervous system involvement of chronic lymphocytic leukaemia: A rare case report. Acta Medica [Internet]. 2024 Jun. 30 [cited 2024 Jul. 25];55(2):145-9. Available from: https://actamedica.org/index.php/actamedica/article/view/994

Issue

Section

Case Report